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Loss of manganese superoxide dismutase leads to abnormal growth and signal transduction in mouse embryonic fibroblasts
Manganese superoxide dismutase (MnSOD) in the mitochondria plays an important role in cellular defense against oxidative damage. Homozygous MnSOD knockout (Sod2(−/−)) mice are neonatal lethal, indicating the essential role of MnSOD in early development. To investigate the potential cellular abnormal...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418666/ https://ncbi.nlm.nih.gov/pubmed/20638473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.07.006 |
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