IL-7Rα(low) memory CD8(+) T cells are significantly elevated in patients with systemic lupus erythematosus

Objective. Human effector memory (EM) CD8(+) T cells include IL-7Rα(high) and IL-7Rα(low) cells with distinct cellular characteristics, including the expression of cytotoxic molecules. Both NK cells and the NK cell-associated molecule 2B4 that is expressed on CD8(+) T cells promote cytotoxicity. Her...

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Dettagli Bibliografici
Autori principali: Kim, Jung-Sik, Cho, Bon-A, Sim, Ji Hyun, Shah, Kamini, Woo, Connie M., Lee, Eun Bong, Lee, Dong-Sup, Kang, Jae Seung, Lee, Wang Jae, Park, Chung-Gyu, Craft, Joe, Kang, Insoo, Kim, Hang-Rae
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418646/
https://ncbi.nlm.nih.gov/pubmed/22661557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/kes100
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