Profiling alterations in platelets induced by Amotosalen/UVA pathogen reduction and gamma irradiation - a LC-ESI-MS/MS-based proteomics approach

BACKGROUND: Pathogen reduction in platelet concentrates (PC) using Amotosalen/UVA-light reduces the risk of transfusion transmitted infections but also decreases the post-transfusion platelet count increment. Little is known about potential platelet lesions caused by Amotosalen/UVA-light, which may...

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Detalhes bibliográficos
Main Authors: Thiele, Thomas, Sablewski, Armin, Iuga, Christina, Bakchoul, Tamam, Bente, Andrea, Görg, Siegfried, Völker, Uwe, Greinacher, Andreas, Steil, Leif
Formato: Artigo
Idioma:Inglês
Publicado em: Edizioni SIMTI — SIMTI Servizi Srl 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418619/
https://ncbi.nlm.nih.gov/pubmed/22890270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2450/2012.010S
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