Functional requirements for inhibitory signal transmission by the immunomodulatory receptor CD300a

BACKGROUND: Activation signals can be negatively regulated by cell surface receptors bearing immunoreceptor tyrosine-based inhibitory motifs (ITIMs). CD300a, an ITIM bearing type I transmembrane protein, is expressed on many hematopoietic cells, including subsets of lymphocytes. RESULTS: We have tak...

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Bibliographic Details
Main Authors: DeBell, Karen E, Simhadri, Venkateswara R, Mariano, John L, Borrego, Francisco
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418551/
https://ncbi.nlm.nih.gov/pubmed/22537350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-13-23
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