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Oncogene-specific formation of chemoresistant murine hepatic cancer stem cells
At least some cancer stem cells (CSCs) display intrinsic drug resistance that may thwart eradication of a malignancy by chemotherapy. We have explored the genesis of such resistance by studying mouse models of liver cancer driven by either MYC or the combination of oncogenic forms of AKT and NRAS. A...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3418440/ https://ncbi.nlm.nih.gov/pubmed/22505225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25776 |
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