Arginylation regulates myofibrils to maintain heart function and prevent dilated cardiomyopathy

Protein arginylation mediated by arginyltransferase (ATE1) is essential for heart formation during embryogenesis, however its cell-autonomous role in cardiomyocytes and the differentiated heart muscle has never been investigated. To address this question, we generated cardiac muscle-specific Ate1 kn...

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Detalhes bibliográficos
Main Authors: Kurosaka, Satoshi, Leu, N. Adrian, Pavlov, Ivan, Han, Xuemei, Ribeiro, Paula Aver Bretanha, Xu, Tao, Bunte, Ralph, Saha, Sougata, Wang, Junling, Cornachione, Anabelle, Mai, Wilfried, Yates, John R, Rassier, Dilson E., Kashina, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418387/
https://ncbi.nlm.nih.gov/pubmed/22626847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.05.007
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