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Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression

Most cells in tissues are polarized and usually have two distinct plasma membrane domains—an apical membrane and a basolateral membrane, which are the result of polarized trafficking of proteins and lipids. However, the mechanism underlying the cell polarization is not fully understood. In this stud...

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Huvudupphovsmän: Yasuda, Takao, Saegusa, Chika, Kamakura, Sachiko, Sumimoto, Hideki, Fukuda, Mitsunori
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418316/
https://ncbi.nlm.nih.gov/pubmed/22767581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-02-0104
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