Heparin Inhibits Hepatocyte Growth Factor Induced Motility and Invasion of Hepatocellular Carcinoma Cells through Early Growth Response Protein 1

The Hepatocyte Growth Factor (HGF)/c-Met signaling pathway regulates hepatocyte proliferation, and pathway aberrations are implicated in the invasive and metastatic behaviors of hepatocellular carcinoma (HCC). In addition to c-Met, heparin acts as a co-receptor to modulate pathway activity. Recently...

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Autori principali: Ozen, Evin, Gozukizil, Aysim, Erdal, Esra, Uren, Aykut, Bottaro, Donald P., Atabey, Nese
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418296/
https://ncbi.nlm.nih.gov/pubmed/22912725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042717
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