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Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine

Coelenterazine is widely distributed among marine organisms, producing bioluminescence by calcium-insensitive oxidation mediated by Renilla luciferase (Rluc) and calcium-dependent oxidation mediated by the photoprotein aequorin. Despite its abundance in nature and wide use of both proteins as report...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Pichler, Andrea, Prior, Julie L., Piwnica-Worms, David
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 2004
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341825/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14755051/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0304326101
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