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IL-3 and TNFα increase Thymic Stromal Lymphopoietin Receptor (TSLPR) expression on eosinophils and enhance TSLP-stimulated degranulation

BACKGROUND: Thymic stromal lymphopoietin (TSLP) and eosinophils are prominent components of allergic inflammation. Therefore, we sought to determine whether TSLP could activate eosinophils, focusing on measuring the regulation of TSLPR expression on eosinophils and degranulation in response to TSLP,...

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Detalhes bibliográficos
Main Authors: Cook, Ellen B, Stahl, James L, Schwantes, Elizabeth A, Fox, Kristen E, Mathur, Sameer K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418208/
https://ncbi.nlm.nih.gov/pubmed/22838633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-7961-10-8
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