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MicroRNA-124 as a novel treatment for persistent hyperalgesia

BACKGROUND: Chronic pain is often associated with microglia activation in the spinal cord. We recently showed that microglial levels of the kinase G protein–coupled receptor kinase (GRK)2 are reduced in models of chronic pain. We also found that mice with a cell-specific reduction of around 50% in G...

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Detalhes bibliográficos
Main Authors: Willemen, Hanneke LDM, Huo, Xiao-Jiao, Mao-Ying, Qi-Liang, Zijlstra, Jitske, Heijnen, Cobi J, Kavelaars, Annemieke
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418202/
https://ncbi.nlm.nih.gov/pubmed/22731384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-143
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