The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner

BACKGROUND: CTCF is a highly conserved and essential zinc finger protein expressed in virtually all cell types. In conjunction with cohesin, it organizes chromatin into loops, thereby regulating gene expression and epigenetic events. The function of CTCFL or BORIS, the testis-specific paralog of CTC...

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Hauptverfasser: Sleutels, Frank, Soochit, Widia, Bartkuhn, Marek, Heath, Helen, Dienstbach, Sven, Bergmaier, Philipp, Franke, Vedran, Rosa-Garrido, Manuel, van de Nobelen, Suzanne, Caesar, Lisa, van der Reijden, Michael, Bryne, Jan Christian, van IJcken, Wilfred, Grootegoed, J Anton, Delgado, M Dolores, Lenhard, Boris, Renkawitz, Rainer, Grosveld, Frank, Galjart, Niels
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418201/
https://ncbi.nlm.nih.gov/pubmed/22709888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-5-8
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