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Production of homoplasmic xenomitochondrial mice

The unique features of mtDNA, together with the lack of a wide range of mouse cell mtDNA mutants, have hampered the creation of mtDNA mutant mice. To overcome these barriers mitochondrial defects were created by introducing mitochondria from different mouse species into Mus musculus domesticus (Mm)...

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Autors principals: McKenzie, Matthew, Trounce, Ian A., Cassar, Carolyn A., Pinkert, Carl A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC341818/
https://ncbi.nlm.nih.gov/pubmed/14745024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0303184101
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