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Elucidation of signaling properties of vasopressin receptor-related receptor 1 by using the chimeric receptor approach

The identification of endogenous or surrogate ligands for orphan G protein-coupled receptors (GPCRs) represents one of the most important tasks in GPCR biology and pharmacology. The challenge lies in choosing an appropriate assay in the absence of ways to activate the receptor of interest. We invest...

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Détails bibliographiques
Auteurs principaux: Gupte, Jamila, Cutler, Gene, Chen, Jin-Long, Tian, Hui
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC341764/
https://ncbi.nlm.nih.gov/pubmed/14757815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308250100
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