טוען...
β-Adrenergic receptors stimulate interleukin-6 production through Epac-dependent activation of PKCδ/p38 MAPK signalling in neonatal mouse cardiac fibroblasts
BACKGROUND AND PURPOSE: IL-6 plays crucial roles in cardiac hypertrophy, cardiac fibrosis and heart failure. Activation of β-adrenoceptors induced IL-6 production in neonatal mouse cardiac fibroblasts (NMCFs) through a G(s)/adenylate cyclase/cAMP/p38 MAPK pathway but independent of PKA. However, how...
שמור ב:
Main Authors: | , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
Blackwell Publishing Ltd
2012
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3417497/ https://ncbi.nlm.nih.gov/pubmed/22103274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01785.x |
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