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The neuroregenerative mechanism mediated by the Hsp90-binding immunophilin FKBP52 resembles the early steps of neuronal differentiation

BACKGROUND AND PURPOSE: The immunosuppressive macrolide FK506 (tacrolimus) shows neuroregenerative action by a mechanism that appears to involve the Hsp90-binding immunophilin FKBP52. This study analyses some aspects of the early steps of neuronal differentiation and neuroregeneration. EXPERIMENTAL...

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Autors principals: Quintá, HR, Galigniana, MD
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417494/
https://ncbi.nlm.nih.gov/pubmed/22091865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01783.x
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