Placebo-Controlled Pilot Trial of Mecamylamine for Treatment of Autism Spectrum Disorders

OBJECTIVE: To explore possible benefits of a nicotinic acetylcholine receptor (nAChR) agent for autistic symptoms based on postmortem observation of nAChR abnormalities (deficient α4β2 nAChRs, excess α7 nAChRs) in brains of patients with autism. METHOD: Mecamylamine, because of its safety record in...

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Detalhes bibliográficos
Main Authors: Arnold, L. Eugene, Aman, Michael G., Hollway, Jill, Hurt, Elizabeth, Bates, Bethany, Li, Xiaobai, Farmer, Cristan, Anand, Rene, Thompson, Susan, Ramadan, Yaser, Williams, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417385/
https://ncbi.nlm.nih.gov/pubmed/22537359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cap.2011.0056
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