Safety and efficacy assessment of the HVTN 503/Phambili Study: A double-blind randomized placebo-controlled test-of-concept study of a Clade B-based HIV-1 vaccine in South Africa

SUMMARY: We report the primary analysis of the safety and efficacy of the MRKad5 gag/pol/nef HIV-1 sub-type B vaccine in South Africa (SA), where the major circulating clade is sub-type C. METHODS: This phase IIb double-blind, randomized test-of-concept study was conducted in sexually active HIV-1 s...

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Huvudupphovsmän: Gray, GE, Allen, M, Moodie, Z, Churchyard, G, Bekker, L-G, Nchabeleng, M, Mlisana, K, Metch, B, de Bruyn, G, Latka, MH, Roux, S, Mathebula, M, Naicker, N, Ducar, C, Carter, DK, Puren, A, Eaton, N, McElrath, MJ, Robertson, M, Corey, L, Kublin, JG
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417349/
https://ncbi.nlm.nih.gov/pubmed/21570355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1473-3099(11)70098-6
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