Itk Functions to Control Actin Polymerization at the Immune Synapse through Localized Activation of Cdc42 and WASP

Actin polymerization at the immune synapse is required for T cell activation and effector function; however, the relevant regulatory pathways remain poorly understood. We showed previously that binding to antigen presenting cells (APCs) induces localized activation of Cdc42 and Wiskott-Aldrich Syndr...

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Detalhes bibliográficos
Main Authors: Labno, Christine M., Lewis, Carol M., You, Daoqi, Leung, Daisy W., Takesono, Ana, Kamberos, Natalie, Seth, Abhinav, Finkelstein, Lisa D., Rosen, Michael K., Schwartzberg, Pamela L., Burkhardt, Janis K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417328/
https://ncbi.nlm.nih.gov/pubmed/13678593
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