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Systemic delivery of a breast cancer-detecting adenovirus using targeted microbubbles
One of the major limitations of cancer gene therapy using recombinant human adenovirus (Ad) is rapid Ad inactivation from systemic delivery. To eliminate this, biotin-coated ultrasound contrast agents, or microbubbles (MBs), were streptavidin-coupled with biotinylated antibodies to three distinct tu...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3417243/ https://ncbi.nlm.nih.gov/pubmed/22653385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2012.29 |
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