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PI3K/AKT pathway alterations are associated with clinically aggressive and histologically anaplastic subsets of pilocytic astrocytoma

Pilocytic astrocytomas (PA) are well-differentiated gliomas having a favorable prognosis when compared with other diffuse or infiltrative astrocytomas. Molecular genetic abnormalities and activation of signaling pathways associated with clinically aggressive PA and histologically anaplastic PA have...

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Detalhes bibliográficos
Main Authors: Rodriguez, Erika F., Scheithauer, Bernd W., Giannini, Caterina, Rynearson, Amanda, Cen, Ling, Hoesley, Bridget, Gilmer-Flynn, Heather, Sarkaria, Jann N., Jenkins, Sarah, Long, Jin, Rodriguez, Fausto J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417062/
https://ncbi.nlm.nih.gov/pubmed/21113787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-010-0784-9
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