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Simplified quantification of labile proton concentration-weighted chemical exchange rate (k(ws)) with RF saturation time dependent ratiometric analysis (QUESTRA) - Normalization of relaxation and RF irradiation spillover effects for improved quantitative chemical exchange saturation transfer (CEST) MRI
Chemical exchange saturation transfer (CEST) MRI is an emerging imaging technique capable of detecting dilute proteins/peptides and microenvironmental properties, with promising in vivo applications. However, CEST MRI contrast is complex, varying not only with the labile proton concentration and exc...
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Autor principal: | |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3417060/ https://ncbi.nlm.nih.gov/pubmed/21842497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.23068 |
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