Structure and Catalytic Mechanism of LigI: Insight into the Amidohydrolase Enzymes of cog3618 and Lignin Degradation()

LigI from Sphingomonas paucimobilis catalyzes the reversible hydrolysis of 2-pyrone-4,6-dicarboxylate (PDC) to 4-oxalomesaconate (OMA) and 4-carboxy-2-hydroxymuconate (CHM) in the degradation of lignin. This protein is a member of the amidohydrolase superfamily of enzymes. The protein was expressed...

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Hauptverfasser: Hobbs, Merlin Eric, Malashkevich, Vladimir, Williams, Howard J., Xu, Chengfu, Sauder, J. Michael, Burley, Stephen K., Almo, Steven C., Raushel, Frank M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416963/
https://ncbi.nlm.nih.gov/pubmed/22475079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300307b
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