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Developmental Trajectory and Environmental Moderation of the Effect of ALDH2 Polymorphism on Alcohol Use

BACKGROUND: In the aldehyde dehydrogenase 2 (ALDH2) gene, the ALDH2*2 allele, prevalent in East Asian populations, encodes an enzyme with severely reduced activity, thereby disrupting the normal metabolism of alcohol. Possession of the ALDH2*2 allele has been repeatedly shown to be associated with l...

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Bibliographic Details
Main Authors: Irons, Daniel E., Iacono, William G., Oetting, William S., McGue, Matt
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416945/
https://ncbi.nlm.nih.gov/pubmed/22563891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2012.01809.x
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