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Sensitivity to TOP2 Targeting Chemotherapeutics Is Regulated by Oct1 and FILIP1L

Topoisomerase II (TOP2) targeting drugs like doxorubicin and etoposide are frontline chemotherapeutics for a wide variety of solid and hematological malignancies, including breast and ovarian adenocarcinomas, lung cancers, soft tissue sarcomas, leukemias and lymphomas. These agents cause a block in...

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Detaylı Bibliyografya
Asıl Yazarlar: Lu, Huarui, Hallstrom, Timothy C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416772/
https://ncbi.nlm.nih.gov/pubmed/22900064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042921
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