Syndecan-2 Is a Novel Target of Insulin-Like Growth Factor Binding Protein-3 and Is Over-Expressed in Fibrosis

Extracellular matrix deposition and tissue scarring characterize the process of fibrosis. Transforming growth factor beta (TGFβ) and Insulin-like growth factor binding protein-3 (IGFBP-3) have been implicated in the pathogenesis of fibrosis in various tissues by inducing mesenchymal cell proliferati...

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Autores principales: Ruiz, Ximena D., Mlakar, Logan R., Yamaguchi, Yukie, Su, Yunyun, Larregina, Adriana T., Pilewski, Joseph M., Feghali-Bostwick, Carol A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416749/
https://ncbi.nlm.nih.gov/pubmed/22900087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043049
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