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Hallmarks of human “immunosenescence”: adaptation or dysregulation?

Is immunosenescence an intrinsic ageing process leading to dysregulation of immunity or an adaptive response of the individual to pathogen exposure? Age-associated differences in bone marrow immune cell output and thymic involution suggest the former. Accepted hallmarks of immunosenescence (decrease...

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Autor principal: Pawelec, Graham
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416738/
https://ncbi.nlm.nih.gov/pubmed/22830639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-9-15
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