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The effects of contig length and depth on the estimation of SNP frequencies, and the relative abundance of SNPs in protein-coding and non-coding transcripts of tiger salamanders (Ambystoma tigrinum)

BACKGROUND: Next-generation sequencing methods have contributed to rapid progress in the fields of genomics and population genetics. Using this high-throughput and cost-effective technology, a number of studies have estimated single nucleotide polymorphism (SNP) frequency by calculating the mean num...

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Détails bibliographiques
Auteurs principaux: Eo, Soo Hyung, DeWoody, J Andrew
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416719/
https://ncbi.nlm.nih.gov/pubmed/22716167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-259
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