Potential novel therapeutic strategies in cystic fibrosis: antimicrobial and anti-biofilm activity of natural and designed α-helical peptides against Staphylococcus aureus, Pseudomonas aeruginosa, and Stenotrophomonas maltophilia

BACKGROUND: Treatment of cystic fibrosis-associated lung infections is hampered by the presence of multi-drug resistant pathogens, many of which are also strong biofilm producers. Antimicrobial peptides, essential components of innate immunity in humans and animals, exhibit relevant in vitro antimic...

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Autors principals: Pompilio, Arianna, Crocetta, Valentina, Scocchi, Marco, Pomponio, Stefano, Di Vincenzo, Valentina, Mardirossian, Mario, Gherardi, Giovanni, Fiscarelli, Ersilia, Dicuonzo, Giordano, Gennaro, Renato, Di Bonaventura, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416647/
https://ncbi.nlm.nih.gov/pubmed/22823964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-12-145
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