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Severe diabetes and leptin resistance cause differential hepatic and renal transporter expression in mice
BACKGROUND: Type-2 Diabetes is a major health concern in the United States and other Westernized countries, with prevalence increasing yearly. There is a need to better model and predict adverse drug reactions, drug-induced liver injury, and drug efficacy in this population. Because transporters sig...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3416584/ https://ncbi.nlm.nih.gov/pubmed/22524730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-5926-11-1 |
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