Loss of Meningococcal PilU Delays Microcolony Formation and Attenuates Virulence In Vivo

Neisseria meningitidis is a major cause of sepsis and bacterial meningitis worldwide. This bacterium expresses type IV pili (Tfp), which mediate important virulence traits such as the formation of bacterial aggregates, host cell adhesion, twitching motility, and DNA uptake. The meningococcal PilT pr...

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Bibliografiske detaljer
Main Authors: Eriksson, Jens, Eriksson, Olaspers Sara, Jonsson, Ann-Beth
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416451/
https://ncbi.nlm.nih.gov/pubmed/22508857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.06354-11
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