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Reclamation of Ampicillin Sensitivity for the Genetic Manipulation of Legionella pneumophila

Research on Legionella pneumophila, the causative agent of Legionnaires' disease, has been hampered due to the lack of selectable markers for genetic manipulation. We report the construction of a mutant strain of L. pneumophila lacking loxA, a chromosomally encoded β-lactamase, that has enhance...

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Detalhes bibliográficos
Main Authors: Sutherland, Molly C., Vogel, Joseph P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416426/
https://ncbi.nlm.nih.gov/pubmed/22635996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00669-12
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