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Development of a Tightly Regulatable Copper-Mediated Gene Switch System in Dermatophytes

Targeted gene deletion is now available for molecular genetic research of dermatophytes, and the physiological roles of several genes have been elucidated. However, this method cannot be applied to essential genes, which can be potential drug targets. To overcome this limitation, we have developed a...

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Autors principals: Iwata, Atsushi, Alshahni, Mohamed Mahdi, Nishiyama, Yayoi, Makimura, Koichi, Abe, Shigeru, Yamada, Tsuyoshi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416413/
https://ncbi.nlm.nih.gov/pubmed/22610431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00464-12
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