Loss of Cytoskeletal Transport during Egress Critically Attenuates Ectromelia Virus Infection In Vivo

Egress of wrapped virus (WV) to the cell periphery following vaccinia virus (VACV) replication is dependent on interactions with the microtubule motor complex kinesin-1 and is mediated by the viral envelope protein A36. Here we report that ectromelia virus (ECTV), a related orthopoxvirus and the cau...

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Main Authors: Lynn, Helena, Horsington, Jacquelyn, Ter, Lee Kuan, Han, Shuyi, Chew, Yee Lian, Diefenbach, Russell J., Way, Michael, Chaudhri, Geeta, Karupiah, Gunasegaran, Newsome, Timothy P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2012
Ábhair:
Pathogenesis and Immunity
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416336/
https://ncbi.nlm.nih.gov/pubmed/22532690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06636-11
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