Envelope Variable Region 4 Is the First Target of Neutralizing Antibodies in Early Simian Immunodeficiency Virus mac251 Infection of Rhesus Monkeys

A major goal of AIDS vaccine development is to design vaccination strategies that can elicit broad and potent protective antibodies. The initial viral targets of neutralizing antibodies (NAbs) early after human or simian immunodeficiency virus (HIV/SIV) infection are not known. The identification of...

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Bibliographic Details
Main Authors: Yeh, Wendy W., Brassard, Laura M., Miller, Caroline A., Basavapathruni, Aravind, Zhang, Jinrong, Rao, Srinivas S., Nabel, Gary J., Mascola, John R., Letvin, Norman L., Seaman, Michael S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416332/
https://ncbi.nlm.nih.gov/pubmed/22532675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00107-12
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