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Cot Kinase Promotes Ca(2+) Oscillation/Calcineurin-Independent Osteoclastogenesis by Stabilizing NFATc1 Protein
Osteoclasts are multinuclear bone-resorbing cells formed by the fusion of monocyte/macrophage-lineage precursor cells. Activation of the transcription factor NFATc1 (nuclear factor of activated T cells c1) by the receptor activator of NF-κB ligand (RANKL) is critical for osteoclast differentiation....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3416192/ https://ncbi.nlm.nih.gov/pubmed/22615493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05611-11 |
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