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Latent HIV-1 Infection Occurs in Multiple Subsets of Hematopoietic Progenitor Cells and Is Reversed by NF-κB Activation

The ability of HIV-1 to establish a latent infection presents a barrier to curing HIV. The best-studied reservoir of latent virus in vivo is resting memory CD4(+) T cells, but it has recently been shown that CD34(+) hematopoietic progenitor cells (HPCs) can also become latently infected by HIV-1 in...

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Detalhes bibliográficos
Main Authors: McNamara, Lucy A., Ganesh, Janani A., Collins, Kathleen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416176/
https://ncbi.nlm.nih.gov/pubmed/22718820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00895-12
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