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Adaptive Changes in Alphavirus mRNA Translation Allowed Colonization of Vertebrate Hosts

Members of the Alphavirus genus are arboviruses that alternate replication in mosquitoes and vertebrate hosts. In vertebrate cells, the alphavirus resists the activation of antiviral RNA-activated protein kinase (PKR) by the presence of a prominent RNA structure (downstream loop [DLP]) located in vi...

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Detalhes bibliográficos
Autor principal: Ventoso, Iván
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416173/
https://ncbi.nlm.nih.gov/pubmed/22761388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01114-12
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