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A Nuclear Localization Signal in Herpesvirus Protein VP1-2 Is Essential for Infection via Capsid Routing to the Nuclear Pore

To initiate infection, herpesviruses must navigate to and transport their genomes across the nuclear pore. VP1-2 is a large structural protein of the virion that is conserved in all herpesviruses and plays multiple essential roles in virus replication, including roles in early entry. VP1-2 contains...

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Detalhes bibliográficos
Main Authors: Abaitua, F., Hollinshead, M., Bolstad, M., Crump, C. M., O'Hare, P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416164/
https://ncbi.nlm.nih.gov/pubmed/22718835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01209-12
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