Hepatitis D Virus Isolates with Low Replication and Epithelial-Mesenchymal Transition-Inducing Activity Are Associated with Disease Remission

Clearance of hepatitis D virus (HDV) viremia leads to disease remission. Large hepatitis delta antigen (L-HDAg) has been reported to activate transforming growth factor β, which may induce epithelial-mesenchymal transition (EMT) and fibrogenesis. This study analyzed serum HDV RNA “quasispecies” in H...

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Autori principali: Shih, Hsuan Hui, Sheen, I-Jane, Su, Chien-Wei, Peng, Wei-Li, Lin, Ling-Hui, Wu, Jaw-Ching
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Genome Replication and Regulation of Viral Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416108/
https://ncbi.nlm.nih.gov/pubmed/22674995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00130-12
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