Analyses of Dynein Heavy Chain Mutations Reveal Complex Interactions Between Dynein Motor Domains and Cellular Dynein Functions

Cytoplasmic dynein transports cargoes for a variety of crucial cellular functions. However, since dynein is essential in most eukaryotic organisms, the in-depth study of the cellular function of dynein via genetic analysis of dynein mutations has not been practical. Here, we identify and characteriz...

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Main Authors: Sivagurunathan, Senthilkumar, Schnittker, Robert R., Razafsky, David S., Nandini, Swaran, Plamann, Michael D., King, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2012
Assuntos:
Investigations
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415999/
https://ncbi.nlm.nih.gov/pubmed/22649085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.141580
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