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The Paf1 Complex Subunit Rtf1 Buffers Cells Against the Toxic Effects of [PSI(+)] and Defects in Rkr1-Dependent Protein Quality Control in Saccharomyces cerevisiae
The Rtf1 subunit of the Paf1 complex is required for specific histone modifications, including histone H2B lysine 123 monoubiquitylation. In Saccharomyces cerevisiae, deletion of RTF1 is lethal in the absence of Rkr1, a ubiquitin-protein ligase involved in the destruction of nonstop proteins, which...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3415995/ https://ncbi.nlm.nih.gov/pubmed/22595241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.141713 |
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