SDHB immunohistochemistry: a useful tool in the diagnosis of Carney–Stratakis and Carney triad gastrointestinal stromal tumors

Mutations in the tumor suppressor genes SDHB, SDHC, and SDHD (or collectively SDHx) cause the inherited paraganglioma syndromes, characterized by pheochromocytomas and paragangliomas. However, other tumors have been associated with SDHx mutations, such as gastrointestinal stromal tumors (GISTs) spec...

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Autors principals: Gaal, José, Stratakis, Constantine A, Carney, J Aidan, Ball, Evan R, Korpershoek, Esther, Lodish, Maya B, Levy, Isaac, Xekouki, Paraskevi, van Nederveen, Francien H, den Bakker, Michael A, O’Sullivan, Maureen, Dinjens, Winand NM, de Krijger, Ronald R
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415983/
https://ncbi.nlm.nih.gov/pubmed/20890271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2010.185
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