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A Functional Single-Nucleotide Polymorphism in the Promoter of the Gene Encoding Interleukin 6 Is Associated With Susceptibility to Tuberculosis

BACKGROUND: Genetic variation influences susceptibility or resistance to tuberculosis. Interleukin 6 (IL-6) contributes to protection against tuberculosis in mice. However, its role in regulating susceptibility or resistance to tuberculosis in humans is unclear. METHODS: Genotyping of polymorphisms...

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Detalhes bibliográficos
Main Authors: Zhang, Guoliang, Zhou, Boping, Wang, Wenfei, Zhang, Mingxia, Zhao, Yahua, Wang, Zheng, Yang, Lin, Zhai, Jingnan, Feng, Carl G., Wang, Junwen, Chen, Xinchun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415858/
https://ncbi.nlm.nih.gov/pubmed/22457277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis266
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