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Protein abundance is key to distinguish promiscuous from functional phosphorylation based on evolutionary information

In eukaryotic cells, protein phosphorylation is an important and widespread mechanism used to regulate protein function. Yet, of the thousands of phosphosites identified to date, only a few hundred at best have a characterized function. It was recently shown that these functional sites are significa...

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Detalhes bibliográficos
Main Authors: Levy, Emmanuel D., Michnick, Stephen W., Landry, Christian R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415844/
https://ncbi.nlm.nih.gov/pubmed/22889910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2012.0078
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