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Synthesis and Cross-Coupling of Secondary Ammoniomethyltrifluoroborates: Rapid and Efficient Access to Secondary Arylmethylamines

Ammoniomethyl trifluoroborates are very powerful reagents that can be used to access biologically relevant aryl- and heteroaryl-methylamine motifs via Suzuki-Miyaura cross-couplings. Until now, this method was limited to the production of tertiary and primary amines. The synthesis of a large array o...

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Detalhes bibliográficos
Main Authors: Fleury-Brégeot, Nicolas, Raushel, Jessica, Sandrock, Deidre L., Dreher, Spencer D., Molander, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415697/
https://ncbi.nlm.nih.gov/pubmed/22767518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201200831
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