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Acidification of the Golgi apparatus is indispensable for maturation but not for cell surface delivery of Ret

We examined the effect of concanamycin A and bafilomycin A1, inhibitors of the vacuolar proton-ATPase, on maturation and expression of Ret, a tyrosine kinase receptor for glial cell line-derived neurotrophic factor. Ret appeared as 150- and 170-kDa bands on sodium dodecyl sulfate–polyacrylamide gel...

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Autors principals: Hirata, Yoko, Shimokawa, Norihiro, Oh-hashi, Kentaro, Yu, Zu-Xi, Kiuchi, Kazutoshi
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415695/
https://ncbi.nlm.nih.gov/pubmed/20796177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06966.x
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