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Regulation of c-Myc Protein Abundance by a Protein Phosphatase 2A–Glycogen Synthase Kinase 3β–Negative Feedback Pathway
Regulation of Myc protein abundance is critical for normal cell growth as evidenced by the fact that deregulated Myc expression is a hallmark of many cancers. One of several important mechanisms that control Myc levels involves its phosphorylation-dependent proteolysis. Previous studies have shown t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3415666/ https://ncbi.nlm.nih.gov/pubmed/22893788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601912448067 |
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