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Genome-Wide Analysis of Germline Signaling Genes Regulating Longevity and Innate Immunity in the Nematode Pristionchus pacificus

Removal of the reproductive system of many animals including fish, flies, nematodes, mice and humans can increase lifespan through mechanisms largely unknown. The abrogation of the germline in Caenorhabditis elegans increases longevity by 60% due to a signal emitted from the somatic gonad. Apart fro...

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Autors principals: Rae, Robbie, Sinha, Amit, Sommer, Ralf J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415453/
https://ncbi.nlm.nih.gov/pubmed/22912581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002864
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