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Mitochondrial Function in Permeabilized Cardiomyocytes Is Largely Preserved in the Senescent Rat Myocardium

The aging heart is characterized by a progressive decline in contractile function and diastolic relaxation. Amongst the factors implicated in these changes is a progressive replacement fibrosis secondary to cardiomyoctye death, oxidative damage, and energetic deficit, each of which may be secondary...

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Библиографические подробности
Главные авторы: Picard, Martin, Wright, Kathryn J., Ritchie, Darmyn, Thomas, Melissa M., Hepple, Russell T.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415432/
https://ncbi.nlm.nih.gov/pubmed/22912774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043003
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